Research Lab of the Pediatrics Center
Clinical Chromatin Biology
NewsResearch ProfileGroup Members
Publications
Contact
 
Publications


Jan Postberg


2011

Schenk R, Jenke A, Zilbauer M, Wirth S, Postberg J. H3.5 is a novel 
hominid-specific histone H3 variant that is specifically expressed in
the
seminiferous tubules of human testes.
Chromosoma; in press.


2010

Zilbauer M, Jenke A, Wenzel G, Goedde D, Postberg J, Phillips AD, 
Lucas M,
Noble-Jamieson G, Torrente F, Salvestrini C, Heuschkel R,
Wirth S. Intestinal
alpha-defensin expression in pediatric
inflammatory bowel disease. Inflamm Bowel
Dis. 2010 Dec 16.


Zilbauer M, Jenke A, Wenzel G, Postberg J, Heusch A, Phillips AD, Noble-Jamieson G, Torrente F, Salvestrini C, Heuschkel R and Wirth S. Expression of human beta-defensins in children with chronic inflammatory bowel disease. PLoS One, 2010 Oct 22;5(10):e15389.


Postberg J, Lipps HJ, Cremer T. Evolutionary origin of the cell nucleus and its functional architecture. Essays Biochem. 2010 Sep 20;48(1):1-24.


Postberg J, Forcob S, Chang WJ, Lipps HJ. The evolutionary history of histone H3 suggests a deep eukaryotic root of chromatin modifying mechanisms. BMC Evol Biol. 2010 Aug 25;10(1):259.


Schaffitzel C, Postberg J, Paeschke K, Lipps HJ. Probing telomeric G-quadruplex DNA structures in cells with in vitro generated single-chain antibody fragments. Methods Mol Biol. 2010;608:159-81.


2009

Jönsson F, Postberg J, and Lipps HJ. The unusual way to make a genetically active nucleus. DNA and Cell Biology, 2009, 28(2), 71-78.    


2008

Postberg J, Heyse K, Cremer M, Cremer T, and Lipps HJ (2008): Spatial and temporal plasticity of chromatin during programmed DNA-reorganization in Stylonychia macronuclear development. Epigenetics & Chromatin, 2008, 1:3.


2007

Stehle IM, Postberg J, Rupprecht S, Cremer T, Jackson DA and Lipps HJ (2007): Establishment and mitotic stability of an extra-chromosomal mammalian replicon. BMC Cell Biology, 2007, 8:33.                             

2006

Postberg J, Alexandrova O, and Lipps HJ (2006): Synthesis of pre-rRNA and mRNA is directed to a chromatin-poor compartment in the macronucleus of the spirotrichous ciliate Stylonychia lemnae. Chromosome Research, 2006, 14(2), 161-175.


Möllenbeck M, Postberg J, Paeschke K, Rossbach M, Jönsson F, Lipps HJ (2006): The end-replication machinery in spirotrichous ciliates. Endocytobiosis and Cell Research, 2006, 17, 111-118.      


2005

Juranek S, Rupprecht S, Postberg J and Lipps HJ (2005): snRNA and heterochromatin formation are involved in DNA excision during macronuclear development in stichotrichous ciliates. Eukaryotic Cell, 2005 November, 4(11), 1934-1941.             


Paeschke K, Simonsson T, Postberg J, Rhodes D and Lipps HJ (2005): Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo. Nature Structural & Molecular Biology, 2005 October, 12(10), 847-854.                 


Postberg J, Alexandrova O, Cremer T and Lipps HJ (2005): Exploiting nuclear duality of ciliates to analyse topological requirements for DNA replication and transcription. Journal of Cell Science, 2005 September, 118(17), 3973-3983.                 


2003

Paschka AG, Jönsson F, Maier V, Möllenbeck M, Paeschke K, Postberg J, Rupprecht S and Lipps HJ (2003): The use of RNAi to analyze gene function in spirotrichous ciliates. European Journal of Protistology, 2003, 39(4), 449-454.


Aigner S, Postberg J, Lipps HJ and Cech T (2003): The Euplotes La motif protein p43 has properties of a telomerase-specific subunit. Biochemistry, 2003 May, 42(19), 5736-47.


Möllenbeck M*, Postberg J*, Paeschke K, Rossbach M, Jönsson F and Lipps HJ (2003): The telomerase associated protein p43 is involved in anchoring telomerase in the nucleus. Journal of Cell Science, 2003 May, 116(9), 1757 1761.         
*Both authors contributed equally.    


Jönsson F, Möllenbeck M, Postberg J and Lipps HJ (2003): The organization of the end-replication machinery in the macronucleus of spirotrichous ciliates. In: Biophysics of the Genome (S. and M. Kozubek, eds.). Masaryk University, Brno, pp. 42-48.


2002

Jönsson F, Postberg J, Schaffitzel C and Lipps HJ (2002): Organization of the macronuclear gene-sized pieces of stichotrichous ciliates into a higher order structure via telomere–matrix interactions. Chromosome Research, 2002, 10(6), 445-453.

       

2001

Schaffitzel C, Berger I, Postberg J, Hanes J, Lipps HJ and Plückthun A (2001). In vitro generated antibodies specific for telomeric guanine-quadruplex DNA react with Stylonychia lemnae macronuclei. Proceedings of the National Academy of Science of the United States of America, 2001 July 17, 98(15), 8572-8577.   


Postberg J, Juranek SA, Feiler S, Kortwig H, Jönsson F, Lipps HJ (2001). Association of the telomere-telomere binding protein-complex of hypotrichous ciliates with the nuclear matrix and dissociation during replication. Journal of Cell Science, 2001 May, 114(10), 1861-1866.


Andreas Jenke


2011

Schenk R, Jenke A, Zilbauer M, Wirth S, Postberg J. H3.5 is a novel 
hominid-specific histone H3 variant that is specifically expressed in
the
seminiferous tubules of human testes.
Chromosoma; in press.


2010

Zilbauer M, Jenke A, Wenzel G, Goedde D, Postberg J, Phillips AD, 
Lucas M,
Noble-Jamieson G, Torrente F, Salvestrini C, Heuschkel R,
Wirth S. Intestinal
alpha-defensin expression in pediatric
inflammatory bowel disease. Inflamm Bowel
Dis. 2010 Dec 16.


Zilbauer M, Jenke A, Wenzel G, Postberg J, Heusch A, Phillips AD, Noble-Jamieson G, Torrente F, Salvestrini C, Heuschkel R and Wirth S. Expression of human beta-defensins in children with chronic inflammatory bowel disease. PLoS One, 2010 Oct 22;5(10):e15389.


Borusiak P, Zilbauer M, Jenke AC. Prevalence of epileptiform discharges in
healthy children--new data from a prospective study using digital EEG. Epilepsia.
2010 Jul;51(7):1185-8.


2009

Jenke AC, Moser S, Orth V, Zilbauer M, Gerner P, Wirth S. Mutation frequency
of NS5A in patients vertically infected with HCV genotype 1 predicts sustained
virological response to peginterferon alfa-2b and ribavirin combination therapy.
J Viral Hepat. 2009 Dec;16(12):853-9.


2008

Jenke, A.C., Wilhelm, A. D., Orth, V., Lipps, H.J., Protzer, U., Wirth, S. (2008) Long term suppression of HBV replication by shRNA expression using the S/MAR based replicating vector system pEPI-1. Antimicrobial agents and chemotherapy, Jul; 52(7): 2355-9.


2006

Gerner, P., Wintermeyer P., Walz, A., Wirth, S and Jenke, A.. (2006). Prevalence of hepatitis C virus infection in children admitted to an urban hospital. J Infect. Apr;52(4):305-8.


2005

Oettinger, R., Brunnberg, A., Gerner, P., Wintermeye,r P., Jenke, A. and Wirth, S. (2005). Clinical features and biochemical data of Caucasian children at diagnosis of autoimmune hepatitis. J Autoimmun. 24(1):79-84.

Jenke, A.C., Eisenberger, T., Baiker, A., Stehle, I.M., Wirth, S. and Lipps, H. (2005). Long term inhibition of bcr-abl gene expression by shRNA using the non-viral episomal replicating vector pEPI-1. Hum Gene Ther. Apr;16(4):533-9.

Wirth, S., Pieper-Boustani, H., Lang, T., Ballauff, A., Kullmer, U., Gerner, P., Wintermeyer, P. and Jenke, A. (2005). Peginterferon alfa-2b Plus Ribavirin Treatment in Children and Adolscents With Chronic Hepatitis C. Hepatology May;41(5):1013-8.

Jenke, A. C., Klein, M., Novotny, E. and Trübel, H. (2005) Approach to the comatose child. Ital J Pediatr 31: 314-324.

 

2004

Jenke, A.C., Scinteie, M.F., Stehle, I. M. and Lipps, H.J. (2004). Expression of a transgene encoded on a non-viral episomal vector is not subject to epigenetic Silencing by cytosine methylation. Mol Bio Rep  31, 85-90.

Jenke, A.C., Stehle I.M., Herrmann, F., Eisenberger, T., Baiker, A., Bode, J., Fackelmayer, F.O. and Lipps, H.J. (2004). Nuclear scaffold/matrix attached region modules linked to a transcription unit are sufficient for replication and maintenance of a mammalian episome. Proc Natl Acad Sci USA 101(31),11322-7.


2003

Lipps, H.J., Jenke, A.C., Nehlsen, K., Scienteie, M., Stehle, I.M. and Bode, J. (2003). Chromosome-Based Vectors For Gene Therapy. Gene 304, 23-33.

Stehle, I.M., Scinteie, M.F., Baiker, A., Jenke, A.C. and Lipps, H.J. (2003). Exploiting a minimal system to study the epigenetic control of DNA replication: the interplay between transcription and replication. Chrom Res. 11(5):413-21.